Medically the evaluation by Alan Carter, Pharm.D. — composed by Jill Seladi-Schulman, Ph.D. Top top December 19, 2018

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Acetaminophen (Tylenol) and ibuprofen (Advil) space both over-the-counter (OTC) drugs that can be supplied to relieve pain.

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These medicines are 2 different varieties of pain relievers. Acetaminophen, sometimes provided as APAP, is its own type, if ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID).

Generally, it’s safe to take it acetaminophen and also ibuprofen together, however you’ll desire to pay close attention to just how much you take it of each medication.

The vital to safely taking acetaminophen and ibuprofen is knowing exactly how much you’re acquisition at a time and also how often.

Acetaminophen dosage

The maximum for sure dosage of acetaminophen for anyone over the period of 12 is 4,000 milligrams (mg) per day. But even this quantity can injury some people’s livers, therefore aim for no an ext than 3,000 mg per day.

For kids under the age of 12, it’s ideal to inspect with their healthcare provider to recognize the safest dose for their body weight.

Keep in psychic that numerous OTC medications contain acetaminophen in a selection of doses, generally 325 mg, 500 mg, or 650 mg.

Some instances of brand-name OTC drugs that may contain paracetamol include:


Remember: as soon as looking at labels, friend might also see acetaminophen noted as APAP.

Ibuprofen dosage

Avoid taking more that 1,200 mg of ibufrofen in a solitary day. OTC ib frames is often uncovered in 200 mg pills. This translates to 6 pills a day. Still, you should always verify just how much is in each pill.

Again, because that children, it’s finest to questioning their medical care provider about the safest sheep for your weight.

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If you have actually prescription-strength ibuprofen, speak to her prescriber before mixing the with any kind of other medications, including acetaminophen.


The recommended boundaries for adults and also children over 12 are:

3,000 mg per day the acetaminophen1,200 mg every day that ibuprofen

For youngsters under the age of 12, contact their medical care provider or describe the product label for dosage guidelines.

You have the right to take ibuprofen and acetaminophen in ~ the very same time. Simply make sure to not take an ext than the recommended dose.

Some civilization experience some stomach or abdominal muscle pain when taking the two drugs together. In this case, it’s much better to alternating when you take each medication.

For example, you could take ibuprofen first, adhered to by acetaminophen four hours later, and then repeat this process as needed.

You could likewise alternate days. For example, if you take ibuprofen ~ above Monday, take acetaminophen on Tuesday and also so on.